Processes involved in the activation of any of the steps of the alternative pathway of the complement cascade which allows for the direct killing of microbes and the regulation of other immune processes.

Processes involved in the activation of any of the steps of the classical pathway of the complement cascade which allows for the direct killing of microbes, the disposal of immune complexes, and the regulation of other immune processes.

Interacting selectively with an insulin-like growth factor, any member of a group of polypeptides that are structurally homologous to insulin and share many of its biological activities, but are immunologically distinct from it.

An immune response mediated through a body fluid.

Interacting selectively with lamin; any of a group of intermediate-filament proteins that form the fibrous matrix on the inner surface of the nuclear envelope.

Interacting selectively with profilin, an actin-binding protein that forms a complex with G-actin and prevents it from polymerizing to form F-actin.

Interacting selectively with tropomyosin, a protein associated with actin filaments both in cytoplasm and, in association with troponin, in the thin filament of striated muscle.

Interacting selectively with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.

Interacting selectively with GTP, guanosine triphosphate.

Interacting selectively with a macrolide, any of a large group of structurally related antibiotics produced by Streptomyces species.

Interacting selectively with the immunosuppressant FK506.

The breakdown into simpler components of any one of a family of organic molecules consisting of a purine or pyrimidine base covalently bonded to a sugar deoxyribose (a deoxyribonucleoside).

Interacting selectively with any mono-, di- or trisaccharide carbohydrate.

A change in state or activity of an organism or cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of exposure to lipid hydroperoxides, the highly reactive primary oxygenated products of polyunsaturated fatty acids.