A multi subunit protease complex located in the endoplasmic reticulum membrane that cleaves the signal sequence from precursor proteins following their transport out of the cytoplasmic space.

The volume enclosed by the membranes of the endoplasmic reticulum.

The lipid bilayer surrounding the endoplasmic reticulum.

A prelysosomal endocytic organelle defined by the time it takes for endocytosed macromolecules to be delivered. The time of delivery may vary ; for example, late endosomes are usually loaded 4-30 min after endocytic uptake in mammalian cells. late endosomes are more spherical than early endosomes and are mostly juxtanuclear, being concentrated near the microtubule organizing center. They are differentiated from early endosomes by their lower lumenal pH and different protein composition.

The whole of the physical, chemical, and biochemical processes carried out by living organisms to break down ingested lipids into components that may be easily absorbed and directed into metabolism.

Catalysis of the reaction: aspartate + H2O + O2 = oxaloacetate + NH3 + H2O2.

The breakdown into simpler components of lipids, as carried out by individual cells.

Catalysis of the hydrolysis of mannosyl compounds, substances containing a group derived from a cyclic form of mannose or a mannose derivative.

A closed structure, found only in eukaryotic cells, that is completely surrounded by unit membrane and contains liquid material.

Catalysis of the hydrolysis of the terminal alpha-D-mannose residues in oligo-mannose oligosaccharides.

The lipid bilayer surrounding the vacuole and separating its contents from the cytoplasm of the cell.

Catalysis of the hydrolysis of galactosyl compounds, substances containing a group derived from a cyclic form of galactose or a galactose derivative.

Catalysis of the hydrolysis of glucosyl compounds, substances containing a group derived from a cyclic form of glucose or a glucose derivative.

Catalysis of the hydrolysis of trehalose or a trehalose derivative.

A small, membrane-bounded organelle that uses dioxygen (O2) to oxidize organic molecules; contains some enzymes that produce and others that degrade hydrogen peroxide (H2O2).