The chemical reactions involving a ribonucleoside diphosphate, a glycosamine consisting of a base linked to a ribose sugar esterified with diphosphate on its glycose moiety.

The chemical reactions involving a deoxyribonucleoside diphosphate, a glycosamine consisting of a base linked to a deoxyribose sugar esterified with diphosphate on its glycose moiety.

The chemical reactions involving a cyclic nucleotide, a nucleotide in which the phosphate group is in diester linkage to two positions on the sugar residue.

negative regulation of lymphocyte activation

Any process that stops, prevents or reduces the rate of lymphocyte activation.

The formation from simpler components of a ribonucleoside diphosphate, a glycosamine consisting of a base linked to a ribose sugar esterified with diphosphate on its glycose moiety.

positive regulation of lymphocyte activation

Any process that activates or increases the rate of lymphocyte activation.

Any process that modulates the frequency, rate or extent of cyclase activity.

The formation from simpler components of a deoxyribonucleoside diphosphate, a glycosamine consisting of a base linked to a deoxyribose sugar esterified with diphosphate on its glycose moiety.

Any process that modulates the frequency, rate or extent of the chemical reactions involving RNA.

The series of events by which a mechanical stimulus is received and converted into a molecular signal.

Any process that stops, prevents or reduces the rate of the chemical reactions involving RNA.

spermidine catabolism to deoxyhypusine, using deoxyhypusine synthase

The breakdown of spermidine to form deoxyhypusine by the enzyme [eIF-5A]-deoxyhypusine synthase. The reaction occurs in four steps: 1. spermidine + NAD+ = dehydrospermidine + NADH + H+; 2. dehydrospermidine + [enzyme]-lysine = 1,3-diaminopropane + [enzyme]-lysine-N6=CH(CH2)3NH2; 3. [enzyme]-lysine-N6=CH(CH2)3NH2 = [eIF-5A]-lysine-N6=CH(CH2)3NH2; 4. [eIF-5A]-lysine-N6=CH(CH2)3NH2 + NADH + H+ = [eIF-5A]-deoxyhypusine + NAD+.

The process of creating protein polymers, compounds composed of a large number of component monomers; polymeric proteins may be made up of different or identical monomers. Polymerization occurs by the addition of extra monomers to an existing poly- or oligomeric protein.