Tethered to a membrane by a covalently attached anchor, such as a lipid moiety, that is embedded in the membrane. When used to describe a protein, indicates that the peptide sequence does not span the membrane.

The larger of the two subunits of an organellar ribosome. Two sites on the ribosomal large subunit are involved in translation: the aminoacyl site (A site) and peptidyl site (P site).

A class of nuclear body; they react against SP100 auto-antibodies (PML, promyelocytic leukemia); cells typically contain 10-30 PML bodies per nucleus; alterations in the localization of PML bodies occurs after viral infection.

Located in the plasma membrane such that some covalently attached portion of the gene product spans or is embedded in one or both leaflets of the membrane.

The chemical reactions involving pyrimidine deoxynucleoside monophosphate, a glycosamine consisting of a pyrimidine base linked to a deoxyribose sugar esterified with phosphate on its glycose moiety.

intrinsic to endoplasmic reticulum membrane

Located in the endoplasmic reticulum membrane such that some covalently attached portion of the gene product spans or is embedded in one or both leaflets of the membrane.

The formation from simpler components of pyrimidine deoxynucleoside monophosphate, a glycosamine consisting of a pyrimidine base linked to a deoxyribose sugar esterified with phosphate on its glycose moiety.

Located in the Golgi membrane such that some covalently attached portion of the gene product spans or is embedded in one or both leaflets of the membrane.

Catalysis of the reaction: L-methionine R-oxide + reduced thioredoxin = L-methionine + oxidized thioredoxin; can act on oxidized methionine in peptide linkage with specificity for the R enantiomer.

Combining with the amino acid gamma-aminobutyric acid (GABA, 4-aminobutyrate) to initiate a change in cell activity. GABA-A receptors function as chloride channels.

The directed movement of polyols, any polyhydric alcohol, into, out of, within or between cells.