The genetically programmed processes that occur during apoptosis.

Catalysis of the reaction: ATP + H2O = ADP + phosphate to directly drive some other reaction, for example ion transport across a membrane.

Interacting selectively with glycine, aminoethanoic acid.

Catalysis of the reaction: ATP + H2O = ADP + phosphate, not directly coupled to any other reaction.

negative regulation of survival gene product activity

negative regulation of survival gene products

Any process that stops, prevents or reduces the rate of survival gene product activity; survival gene products are those that antagonize the apoptotic program. Regulation can be at the transcriptional, translational, or posttranslational level.

Interacting selectively with glutamate, the anion of 2-aminopentanedioic acid.

ATPase activity, coupled to transmembrane movement of ions

Catalysis of the reaction: ATP + H2O = ADP + phosphate, to directly drive the transport of ions across a membrane.

Upregulation of the activity of a caspase, any of a group of cysteine proteases involved in apoptosis, mediated by cytochrome c.

A heterodimeric complex comprising BRCA1 and BARD1, which possesses ubiquitin ligase activity and is involved in genome maintenance, possibly by functioning in surveillance for DNA damage.

ATPase activity, coupled to transmembrane movement of substances

Catalysis of the reaction: ATP + H2O = ADP + phosphate to directly drive the transport of a substance across a membrane.

Citrate lyase is a multienzyme complex with three constituents: the alpha subunit, citrate-ACP transferase; the beta subunit, citryl-ACP lyase; and the gamma subunit, an acyl-carrier protein which also carries the prosthetic group components. All three subunits are required for citrate lyase enzyme activity.

Interacting selectively with an amino acid, organic acids containing one or more amino substituents.

A particle composed of a central core of triglycerides surrounded by a protein-phospholipid coating. Chylomicrons are found in blood or lymph and carry lipids from the intestines into other body tissues.