Catalysis of the reaction: (S)-lactate + NAD+ = pyruvate + NADH + H+.

Catalysis of the stereospecific transfer of amino acids, organic acids containing one or more amino substituents, across a biological membrane.

negative regulation of bone mineralization

Any process that stops, prevents or reduces the rate of bone mineralization.

Any process that modulates the redox environment of a cell or compartment within a cell.

Catalysis of the transfer of inorganic diphosphate across a membrane.

Interacting selectively with ankyrin, a 200 kDa cytoskeletal protein that attaches other cytoskeletal proteins to integral membrane proteins.

Interacting selectively with spectrin, a protein that is the major constituent of the erythrocyte cytoskeletal network. It associates with band 4.1 (see band protein) and actin to form the cytoskeletal superstructure of the erythrocyte plasma membrane. It is composed of nonhomologous chains, alpha and beta, which aggregate side-to-side in an antiparallel fashion to form dimers, tetramers, and higher polymers.

Functions as an exchange intermediate in thiol-disulfide exchange reactions.

Interacting selectively with TRAIL (TNF-related apoptosis inducing ligand), a member of the tumor necrosis factor ligand family that rapidly induces apoptosis in a variety of transformed cell lines.

A series of molecular signals generated as a consequence of any member of the BMP (bone morphogenetic protein) family binding to a cell surface receptor.

Catalysis of the reaction: sulfate(out) + Na+(out) = sulfate(in) + Na+(in).

Catalysis of the reaction: GTP + (5')PP-pur-mRNA = diphosphate + G(5')PPP-pur-mRNA (mRNA containing a guanosine residue linked 5' through three phosphates to the 5' position of the terminal residue).

Catalysis of the reaction: ATP + 3-methylcrotonyl-CoA + HCO3- = ADP + phosphate + 3-methylglutaconyl-CoA.

Catalysis of the reaction: Na+(out) + H+(in) = Na+(in) + H+(out).

Catalysis of the reaction: 5,10-methylenetetrahydrofolate + NAD(P)+ = 5,10-methenyltetrahydrofolate + NAD(P)H + H+.