Combining with an extracellular or intracellular messenger, and in cooperation with a nearby primary receptor, initiating a change in cell activity.

Any process that stops, prevents or reduces the rate of transcription.

Catalysis of the reaction: S-adenosyl-L-methionine + arsenite = S-adenosyl-L-homocysteine + methylarsonate.

The directed movement of substances (such as macromolecules, small molecules, ions) into, out of, or within the cytoplasm of a cell.

Catalysis of the reaction: S-adenosyl-L-methionine + methylarsonite = S-adenosyl-L-homocysteine + dimethylarsinate.

A part of the respiratory chain, containing about 10 polypeptide subunits including four redox centers: cytochrome b/b6, cytochrome c1 and an 2Fe-2S cluster. Catalyzes the oxidation of ubiquinol by oxidized cytochrome c1.

The post translational modification of a protein, particularly secretory proteins and proteins targeted for membranes or specific cellular locations.

The generation of a mature peptide hormone by posttranslational processing of a prohormone.

A part of the respiratory chain, containing the 13 polypeptide subunits of cytochrome c oxidase, including cytochrome a and cytochrome a3. Catalyzes the oxidation of reduced cytochrome c by dioxygen (O2).

The rapid expansion of a lymphocyte population by cell division.

The process whose specific outcome is the progression of the skeleton over time, from its formation to the mature structure. The skeleton is the bony framework of the body in vertebrates (endoskeleton) or the hard outer envelope of insects (exoskeleton or dermoskeleton).

The formation from simpler components of the heparan sulfate proteoglycan, a glycosaminoglycan with repeat unit consisting of alternating (alpha1-

The chemical reactions involving tetrahydrofolate, 5,6,7,8-tetrahydrofolic acid, a folate derivative bearing additional hydrogens on the pterin moiety.

The formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone or a bony substance.

heparan sulfate proteoglycan biosynthesis, polysaccharide chain biosynthesis