The formation from simpler components of fractalkine, a chemokine involved in the control of the key regulatory mechanisms of cell trafficking at sites of inflammation. It exists as a secreted protein and in a membrane-bound form, and exhibits a novel C-X-X-X-C cysteine signature motif. The counterpart of human fractalkine is murine neurotactin; fractalkine is also referred to as CX3C membrane-anchored chemokine or ABCD-3 and has been renamed CX3CL1.

The change in morphology and behavior of alpha-beta T cells resulting from exposure to a mitogen or to an antigen to which they have been primed.

Any process that modulates the frequency, rate or extent of the formation from simpler components of fractalkine, a chemokine involved in the control of the key regulatory mechanisms of cell trafficking at sites of inflammation.

The rapid expansion of an alpha-beta T cell population by cell division.

positive regulation of fractalkine biosynthesis

positive regulation of neurotactin biosynthesis

Any process that activates or increases the rate of the formation from simpler components of fractalkine, a chemokine involved in the control of the key regulatory mechanisms of cell trafficking at sites of inflammation.

regulation of alpha-beta T cell activation

regulation of alpha-beta T-lymphocyte activation

Any process that modulates the frequency, rate or extent of alpha-beta T cell activation.

Interacting selectively with a G-protein-coupled receptor.

The chemical reactions involving chemokines, any of a subgroup of cytokines which act primarily on hemopoietic cells in acute and inflammatory processes and other immunoregulatory functions.

positive regulation of alpha-beta T cell activation

positive regulation of alpha-beta T-lymphocyte activation

Any process that activates or increases the rate of alpha-beta T cell activation.

Catalysis of the reaction: CMP-N-acetylneuraminate + glycano-1,3-(N-acetyl-alpha-D-galactosaminyl)-glycoprotein = CMP + glycano-(2,6-alpha-N-acetylneuraminyl)-(N-acetyl-D-galactosaminyl)-glycoprotein.