The formation from simpler components of platelet activating factor, 1-O-alkyl-2-acetyl-sn-glycerol 3-phosphocholine, where alkyl = hexadecyl or octadecyl. Platelet activating factor is an inflammatory mediator released from a variety of cells in response to various stimuli.

The chemical reactions involving glycolipids, compounds containing (usually) 1-4 linked monosaccharide residues joined by a glycosyl linkage to a lipid.

A change in state or activity of a cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the perception of an external stimulus.

negative regulation of transcriptional preinitiation complex formation

negative regulation of transcriptional pre-initiation complex formation

Any process that stops, prevents or reduces the rate of transcriptional preinitiation complex formation.

The chemical reactions involving sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid).

The action of a molecule that contributes to the structural integrity of the nuclear pore complex.

A change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the perception of a biotic stimulus.

Catalysis of the reaction: 6-phospho-D-glucono-1,5-lactone + H2O = 6-phospho-D-gluconate.

The chemical reactions involving sphinganine, D-erythro-2-amino-1,3-octadecanediol.

The chemical reactions involving sphinganine-1-phosphate, the phosphorylated derivative of D-erythro-2-amino-1,3-octadecanediol.

Combining with interleukin-10 to initiate a change in cell activity.

The formation from simpler components of sphinganine-1-phosphate, the phosphorylated derivative of D-erythro-2-amino-1,3-octadecanediol.

leukemia inhibitory factor receptor activity

Combining with leukemia inhibitory factor to initiate a change in cell activity.

Combining with oncostatin-M to initiate a change in cell activity.

Combining with prolactin to initiate a change in cell activity.