An assembly of six molecules of connexin, made in the Golgi apparatus and subsequently transported to the plasma membrane, where docking of two connexons on apposed plasma membranes across the extracellular space forms a gap junction.

The morphological and physiological alterations undergone by the nucleus during apoptosis.

A belt-like region of very close contact between the plasma membranes of adjacent cells so that the intercellular space is completely occluded. They occur in epithelia and brain endothelia.

The compaction of chromatin during apoptosis.

Catalysis of the reaction: phosphatidylinositol-3,4,5-trisphosphate + H2O = phosphatidyl inositol-4,5-bisphosphate + phosphate.

An adherens junction which connects a cell to the extracellular matrix.

Small region on the surface of a cell that anchors the cell to the extracellular matrix and that are points of termination of actin filaments.

Catalysis of the reaction: glycolate + NADP+ = glyoxylate + NADPH + H+.

The formation from simpler components of sphingoids, any of a class of compounds comprising sphinganine and its homologues and stereoisomers, and derivatives of these compounds.

The breakdown into simpler components of sphingoids, any of a class of compounds comprising sphinganine and its homologues and stereoisomers, and derivatives of these compounds.

A specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole.

Catalysis of the reaction: UDP-galactose + O-beta-D-xylosylprotein = UDP + 4-beta-D-galactosyl-O-beta-D-xylosylprotein.

Combining with angiotensin to initiate a change in cell activity.

Catalysis of the transfer of a glucosyl group to an acceptor molecule, typically another carbohydrate or a lipid.

Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate (PAPS) + keratan = adenosine 3',5'-bisphosphate + keratan 6'-sulfate.