Catalysis of the hydrolysis of alpha-(2-

Catalysis of the initiation of the NEDD8 (RUB1) conjugation cascade.

The breakdown into simpler components of chitin, a linear polysaccharide consisting of P-1,4-linked N-acetyl-D-glucosamine residues.

Catalysis of the hydrolysis of various forms of polymeric ubiquitin-like sequences (e.g. APG8, ISG15, NEDD8, SUMO). Will remove ubiquitin-like sequences from larger leaving groups.

The breakdown into simpler components of bile acids, any of a group of steroid carboxylic acids occurring in bile.

Catalysis of the hydrolysis of NEDD8, a small ubiquitin-related modifier, from previously neddylated substrates.

The proteolytic breakdown into simpler components of collagen in the extracellular matrix, usually carried out by proteases secreted by nearby cells.

nuclear body organization and biogenesis

nuclear body organisation and biogenesis

The assembly and arrangement of any of the extra-nucleolar nuclear domains usually visualized by confocal microscopy and fluorescent antibodies to specific proteins.

The assembly and arrangement of PML bodies, a class of nuclear body; they react against SP100 auto-antibodies (PML = promyelocytic leukemia).

Interacting selectively with any monosaccharide. Monosaccharides are the simplest carbohydrates; they are polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms. They form the constitutional repeating units of oligo- and polysaccharides.

Catalysis of ATP-dependent isopeptide bond formation between the carboxy terminal glycine residues of the small ubiquitin-related modifier, SUMO, and a substrate lysine residue, leading to the formation of predominately monosumoylated proteins with modified function.

The process by which the migration of an axon growth cone is directed to a specific target site in response to a combination of attractive and repulsive cues.

Catalysis of the reaction: a glycerophosphodiester + H2O = an alcohol + sn-glycerol 3-phosphate.

The process by which an axon recognizes and binds to a set of cells with which it may form stable connections.