The repair of double-strand breaks in DNA via homologous and nonhomologous mechanisms to reform a continuous DNA helix.

positive regulation of microtubule polymerization or depolymerization

Any process that activates or increases the rate of microtubule polymerization or depolymerization.

The process whereby a relatively unspecialized cell acquires the specialized features of a mesoderm cell.

double-strand break repair via nonhomologous end-joining

The repair of a double-strand break in DNA in which the two broken ends are rejoined with little or no sequence complementarity. Information at the DNA ends may be lost due to the modification of broken DNA ends.

Any process that modulates the frequency, rate or extent of microtubule polymerization.

The covalent or conformational alteration of one or more nucleotide sites in DNA, resulting in a change in its properties.

Any process that modulates the frequency, rate or extent of microtubule depolymerization.

The addition of alkyl groups to many positions on all four bases of DNA. Alkylating agents can also modify the bases of incoming nucleotides in the course of DNA synthesis.

negative regulation of microtubule polymerization

Any process that stops, prevents or reduces the rate of microtubule polymerization.

The covalent transfer of a methyl group to either N-6 of adenine or C-5 or N-4 of cytosine.

positive regulation of microtubule polymerization

Any process that activates or increases the rate of microtubule polymerization.

The repair of alkylation damage, e.g. the removal of the alkyl group at the O6-position of guanine by O6-alkylguanine-DNA alkyltransferase (AGT).

The directed movement of substances into the nucleus.

The breakdown into simpler components of DNA, deoxyribonucleic acid, one of the two main types of nucleic acid, consisting of a long unbranched macromolecule formed from one or two strands of linked deoxyribonucleotides, the 3'-phosphate group of each constituent deoxyribonucleotide being joined in 3',5'-phosphodiester linkage to the 5'-hydroxyl group of the deoxyribose moiety of the next one.