negative regulation of fibroblast proliferation

Any process that stops, prevents or reduces the rate of multiplication or reproduction of fibroblast cells.

Any process that establishes and transmits the specification of sexual status of an individual organism.

Catalysis of the reaction: orotidine 5'-phosphate = UMP + CO2.

Catalysis of the reaction: 2-oxoglutarate + lipoamide = S-succinyldihydrolipoamide + CO2.

The directed movement of a drug, a substance used in the diagnosis, treatment or prevention of a disease, into, out of, within or between cells.

Catalysis of the reaction: ATP + pantothenate = ADP + D-4'-phosphopantothenate.

Catalysis of the reaction: ATP + pantetheine 4'-phosphate = diphosphate + dephospho-CoA.

Catalysis of the reaction: acetyl-CoA + peptide = CoA + N-alpha-acetylpeptide.

Catalysis of the reaction: peptide L-aspartate + 2-oxoglutarate + O2 = peptide 3-hydroxy-L-aspartate + succinate + CO2.

The directed movement amiloride into, out of, within or between cells. Amiloride is a potent and specific inhibitor of sodium ion entry into cells. It is used as a potassium-sparing diuretic.

The formation from simpler components of a pyrimidine ribonucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a ribose sugar) esterified with a phosphate moiety at either the 3' or 5'-hydroxyl group of its glycose moiety.

tricarboxylic acid cycle intermediate metabolism

citric acid cycle intermediate metabolism

The chemical reactions involving intermediates of the tricarboxylic acid cycle.

Catalysis of the reaction: peptidylamidoglycolate = peptidyl amide + glyoxylate.

Any process that modulates the occurrence or rate of cell death by apoptosis.

The formation from simpler components of a pyrimidine deoxyribonucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a deoxyribose sugar) esterified with a phosphate moiety at either the 3' or 5'-hydroxyl group of its glycose moiety.

The chemical reactions involving citrate, 2-hydroxy-1,2,3-propanetricarboyxlate. Citrate is widely distributed in nature and is an important intermediate in the TCA cycle and the glyoxylate cycle.