di-, tri-valent inorganic anion homeostasis

The regulation of the levels, transport, and metabolism of divalent and trivalent inorganic anions within a cell or between a cell and its external environment.

Catalysis of the reaction: ADP-ribose + H2O = AMP + D-ribose 5-phosphate.

Catalysis of the hydroxylation of C-25 of calciferol (vitamin D3) to form 25-hydroxycalciferol.

A thin layer of dense material found in various animal tissues interposed between the cells and the adjacent connective tissue. It consists of the basal lamina plus an associated layer of reticulin fibers.

A thin sheet of proteoglycans and glycoproteins, especially laminin, secreted by cells as an extracellular matrix.

The action of a molecule that contributes to the structural integrity of tooth enamel.

A large, extracellular glycoprotein complex composed of three different polypeptide chains, alpha1, beta1 and gamma1.

Catalysis of the reaction: ATP + tau-protein = ADP + O-phospho-tau-protein.

Either of the ends of a spindle, where spindle microtubules are organized; usually contains a microtubule organizing center and accessory molecules, spindle microtubules and astral microtubules.

The breakdown into simpler components of spermidine, N-(3-aminopropyl)-1,4-diaminobutane.

Catalysis of the reaction: testosterone + NAD+ = androst-4-ene-3,17-dione + NADH.

The breakdown into simpler components of spermine, a polybasic amine found in human sperm, in ribosomes and in some viruses and involved in nucleic acid packaging.

DNA damage response, signal transduction by p53 class mediator

A cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the perception of DNA damage.

The chemical reactions involving nitric oxide, nitrogen monoxide (NO), a colorless gas only slightly soluble in water.

Interacting selectively with cyclins, proteins whose levels in a cell varies markedly during the cell cycle, rising steadily until mitosis, then falling abruptly to zero. As cyclins reach a threshold level, they are thought to drive cells into G2 phase and thus to mitosis.