Rac guanyl-nucleotide exchange factor activity

Stimulates the hydrolysis and exchange of guanyl nucleotides by the GTPase Rac.

A signal transduction based surveillance mechanism that prevents the initiation of mitosis until DNA replication is complete, thereby ensuring that progeny inherit a full complement of the genome.

antigen processing, exogenous antigen via MHC class II

antigen processing, exogenous antigen via major histocompatibility complex class II

The processes that result in the fragmentation by proteolysis of exogenous antigens and the association of the resulting peptides with MHC class II molecules.

A ribonucleoprotein complex that catalyzes cleavage of the leader sequence of precursor tRNAs (pre-tRNAs), generating the mature 5' end of tRNAs.

DNA damage response, signal transduction resulting in cell cycle arrest

A signal transduction pathway, induced by DNA damage, that blocks cell cycle progression (in G1, G2 or metaphase) or slows the rate at which S phase proceeds.

Modulates the activity of a protein kinase, an enzyme which phosphorylates a protein.

The formation from simpler components of chondroitin sulfate proteoglycan, any glycoprotein whose glycosaminoglycan units are chondroitin sulfate. Chondroitin sulfates are a group of 10-60 kDa glycosaminoglycans, widely distributed in cartilage and other mammalian connective tissues; the repeat units consist of beta-(1,4)-linked D-glucuronyl beta-(1,3)-N-acetyl-D-galactosamine sulfate.

Any small opening in a membrane that allows the passage of gases and/or liquids.

Modulation of the activity of a protein phosphatase enzyme.

The formation from simpler components of dermatan sulfate proteoglycan, any glycoprotein whose glycosaminoglycan units are dermatan sulfate (chondroitin sulfate B). Dermatan sulfate is a glycosaminoglycan with repeats consisting of beta-(1,4)-linked L-iduronyl-beta-(1,3)-N-acetyl-D-galactosamine 4-sulfate units.

regulation of cyclin dependent protein kinase activity

Any process that modulates the frequency, rate or extent of CDK activity.