The chemical reactions involving rRNA, ribosomal RNA, a structural constituent of ribosomes.

Ribonucleoprotein complex containing small nuclear RNA U5; a component of both the major and minor spliceosome complexes.

A ribonucleoprotein complex, that includes the U7 snRNA, required for the 3'-end processing of replication dependent histone pre-mRNAs.

The chemical reactions involving snoRNA, small nucleolar RNA, any of a class of small RNAs that are associated with the eukaryotic nucleus as components of small nucleolar ribonucleoproteins. They participate in the processing of ribosomal RNA, and they contain a long stretch of sequence complementarity to conserved sequences in mature mRNA.

The major (U2-dependent) spliceosome is composed of five snRNP complexes (U1, U2, U4, U5, and U6) as well as many non-snRNP proteins. It acts through many RNA-RNA, RNA-protein, and protein-protein interactions to precisely excise each intron and join the flanking exons.

Ribonucleoprotein complex containing small nuclear RNA U2; a component of the major spliceosome complex.

Catalysis of the hydrolysis of alpha-L-iduronosidic linkages in desulfated dermatan.

Fusion of intracellular membrane-bound vesicles with the pre-synaptic membrane of the neuronal cell resulting in release of neurotransmitter into the synaptic cleft.

The minor (U12-dependent) spliceosome is composed of the snRNPs, U11, U12, U4atac, U6atac, and U5 (which is also a component of the major spliceosome). This minor form of the spliceosome is responsible for the splicing of the majority of introns with atypical AT-AC terminal dinucleotides, as well as other non-canonical introns. The entire splice site signal, not just the terminal dinucleotides, is involved in determining which spliceosome utilizes the site.

Catalysis of the reaction: L-serine = pyruvate + NH3.

Catalysis of the hydrolysis of the 4-sulfate groups of the N-acetyl-D-galactosamine 4-sulfate units of chondroitin sulfate and dermatan sulfate.

Modulates the activity of any of the phosphoinositide 3-kinases (PI3Ks). Regulatory subunits can link a PI3K catalytic subunit to upstream signaling events and help position the catalytic subunits close to their lipid substrates.