Catalysis of the reaction: DNA (containing 6-O-methylguanine) + (protein)-L-cysteine = DNA (without 6-O-methylguanine) + protein S-methyl-L-cysteine.

Catalysis of the formation of a phosphodiester bond between the 3'-hydroxyl group at the end of one DNA chain and the 5'-phosphate group at the end of another; requires an energy source such as ATP or NAD+.

Antagonizes ribosome-mediated translation of mRNA into a polypeptide.

ligand-dependent nuclear receptor transcription coactivator activity

ligand-dependent nuclear receptor transcription co-activator activity

The envelope that surrounds the nucleus of eukaryotic cells. It is a double membrane composed of two lipid bilayers separated by a gap of width 20-40 nm (the perinuclear space).

thyroid hormone receptor coactivator activity

thyroid hormone receptor co-activator activity

Receptor that anchors ribosomes to the endoplasmic reticulum (ER) membrane during protein translocation into the ER.

The inner lipid bilayer of the nuclear envelope.

Any of a group of intermediate-filament proteins that form the fibrous matrix on the inner surface of the nuclear envelope. They are classified as lamins A, B and C.

Fibers, composed of actin, myosin, and associated proteins, found in cells of smooth or striated muscle.

Catalysis of the reaction: N6,N6,N6-trimethyl-L-lysine + 2-oxoglutarate + O2 = 3-hydroxy-N6,N6,N6-trimethyl-L-lysine + succinate + CO2.

A multisubunit protein complex involved in the activation of apoptosis. In mammals it is typically composed of seven Apaf-1 subunits bound to cytochrome c and caspase-9. A similar complex to promote apoptosis is formed from homologous gene products in other eukaryotic organisms.

Catalysis of the addition of a phosphate group to an inositol lipid at the 3' position of the inositol ring to generate the 3-phosphoinositides: phosphatidylinositol-3-phosphate [PI(3)P], phosphatidylinositol-3,4-bisphosphate [PI(3,4)P2] and phosphatidylinositol-3,4,5-trisphosphate [PI(3,4,5)P3].

Catalysis of the reaction: triphosphate + H2O = diphosphate + phosphate.