Catalysis of the endonucleolytic cleavage of RNA-DNA hybrids to 5'-phosphomonoesters.

Catalysis of the endonucleolytic cleavage of RNA to 5'-phosphomonoesters; cleaves multimeric tRNA precursor at the spacer region; also involved in processing of precursor rRNA, hnRNA and early T7-mRNA; also cleaves double-stranded DNA.

Catalysis of the endonucleolytic cleavage of RNA, removing 5' extra nucleotides from tRNA precursor.

Catalysis of the hydrolysis of ester linkages within nucleic acids by removing nucleotide residues from the 3' or 5' end.

Catalysis of the sequential hydrolytic removal of 5'-nucleotides from the 3'-hydroxy termini of 3'-hydroxy-terminated oligonucleotides.

Catalysis of the sequential cleavage of mononucleotides from a free 5' or 3' terminus of a DNA molecule.

The directed movement of L-aspartate, the levorotatory isomer of the anion of aspartic acid, into, out of, within or between cells.

Catalysis of the reaction: L-tryptophan + tetrahydropteridine + O2 = 5-hydroxy-L-tryptophan + dihydrobiopterin + H2O.

The chemical reactions involving DNA, deoxyribonucleic acid, one of the two main types of nucleic acid, consisting of a long, unbranched macromolecule formed from one, or more commonly, two, strands of linked deoxyribonucleotides.

Catalysis of the reaction: L-tyrosine + tetrahydrobiopterin + O2 = 3,4-dihydroxy-L-phenylalanine + dihydrobiopterin + H2O.

Catalysis of the reaction: D-glucose 6-phosphate = 1D-myo-inositol 3-phosphate; requires NAD, which dehydrogenates the CHOH group to CO at C-5 of the glucose 6-phosphate, making C-6 into an active methylene, able to condense with the aldehyde at C-1. Finally, the enzyme-bound NADH reconverts C-5 into the CHOH form.

The directed movement of L-glutamate, the levorotatory isomer of the anion of 2-aminopentanedioic acid, into, out of, within or between cells.

Catalysis of the reaction: nicotinate D-ribonucleotide + diphosphate + CO2 = pyridine-2,3-dicarboxylate + 5-phospho-alpha-D-ribose 1-diphosphate.

The directed movement of glycine, aminoethanoic acid, into, out of, within or between cells.