oxidized base lesion DNA N-glycosylase activity

Catalysis of the removal of oxidized bases by cleaving the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar. The reaction releases a free base and leaves an apurinic/apyrimidinic (AP) site.

Interacting selectively with an antigen, any substance which is capable of inducing a specific immune response and of reacting with the products of that response, the specific antibody or specifically sensitized T-lymphocytes, or both. Binding may counteract the biological activity of the antigen.

Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + alpha-D-mannosyl-1,3-(R1)-beta-D-mannosyl-R2 = UDP + N-acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl-1,3-(R1)-beta-D-mannosyl-R2.

Catalysis of the reaction: CMP-N-acetylneuraminate + alpha-N-acetylneuraminyl-2,3-beta-D-galactosyl-R = CMP + alpha-N-acetylneuraminyl-2,8-alpha-N-acetylneuraminyl-2,3-beta-D-galactosyl-R.

Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + beta-D-galactosyl-1,3-N-acetyl-D-galactosaminyl-R = UDP + beta-D-galactosyl-1,3-(N-acetyl-beta-D-glucosaminyl-1,6)-N-acetyl-D-galactosaminyl-R.

Blocks the binding of interleukin-1 to the interleukin-1 receptor complex.

Interacting selectively with the interleukin-8 receptor.

Interacting selectively with the insulin receptor.

Catalysis of the formation of the N6-(L-isoglutamyl)-L-lysine isopeptide, resulting in cross-linking polypeptide chains; the gamma-carboxamide groups of peptidyl-glutamine residues act as acyl donors, and the 6-amino-groups of peptidyl-lysine residues act as acceptors, to give intra- and intermolecular N6-(5-glutamyl)lysine cross-links.

insulin-like growth factor receptor binding

insulin-like growth factor receptor ligand

Interacting selectively with the insulin-like growth factor receptor.

Catalysis of the cleavage of Arg-Ser bond in complement component C3 alpha-chain to yield C3a and C3b, and Arg bond in complement component C5 alpha-chain to yield C5a and C5b.

Catalysis of the selective cleavage of Arg-Ser bond in complement component C3 alpha-chain to form C3a and C3b, and Arg bond in complement component C5 alpha-chain to form C5a and C5b.