DNA-directed RNA polymerase II, holoenzyme

Large protein complex composed of the RNA polymerase core complex and a variety of other proteins including transcription factor complexes TFIIA, D, E, F, and H which are required for promoter recognition, and the Mediator subcomplex. Catalyzes the synthesis of eukaryotic pre-mRNA.

induction of apoptosis by oxidative stress

The activation, by oxidative stress, of any of the steps required for cell death by apoptosis.

Enables the directed movement of oxalate into, out of, within or between cells. Oxalate, or ethanedioic acid, occurs in many plants and is highly toxic to animals.

A multimeric enzyme complex that in E. coli is an heterooctamer made up of four alpha subunits and four beta subunits. Catalyzes the hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D-galactosides.

The genetically programmed processes that occur during apoptosis.

The directed movement of oxalate into, out of, within or between cells. Oxalate, or ethanedioic acid, occurs in many plants and is highly toxic to animals.

Catalysis of the reaction: ATP + H2O = ADP + phosphate to directly drive some other reaction, for example ion transport across a membrane.

activation of pro-apoptotic gene products

induction of pro-apoptotic gene products

The conversion of proteins that induce or sustain apoptosis to an active form.

An enzyme complex that catalyzes the formation of carboxybiotin-carboxyl-carrier protein from biotin-carboxyl-carrier protein and carbon dioxide (CO2).

Catalysis of the reaction: ATP + H2O = ADP + phosphate, not directly coupled to any other reaction.

negative regulation of survival gene product activity

negative regulation of survival gene products

Any process that stops, prevents or reduces the rate of survival gene product activity; survival gene products are those that antagonize the apoptotic program. Regulation can be at the transcriptional, translational, or posttranslational level.

ATPase activity, coupled to transmembrane movement of ions