The process whose specific outcome is the progression of the myeloid and lymphoid derived organ/tissue systems of the blood and other parts of the body over time, from formation to the mature structure. The site of hemopoiesis is variable during development, but occurs primarily in bone marrow or kidney in many adult vertebrates.

The process whereby a relatively unspecialized precursor cell acquires specialized features of B cells, T cells, or natural killer cells.

energy coupled proton transport, against electrochemical gradient

The space between the mitochondrial outer membrane and inner membrane.

The process whereby a relatively unspecialized myeloid precursor cell acquires the specialized features of an erythrocyte, megakaryocyte, platelet, basophil, eosinophil, neutrophil, monocyte, macrophage, or osteoclast cell.

The formation from simpler components of disaccharides, sugars composed of two monosaccharide units.

The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes concerned with fatty-acid oxidation and enzymes of the tricarboxylic acid cycle.

The breakdown into simpler components of acetyl-CoA, a derivative of coenzyme A in which the sulfhydryl group is acetylated.

The material contained within the membrane of a peroxisome; in many cells the matrix contains a crystalloid core largely composed of urate oxidase.

The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).

A translocation complex that constitutes the specific site of protein translocation across the endoplasmic reticulum, which involves the signal recognition particle receptor. Composed of a heterotetramer of alpha, beta, gamma and delta subunits (translocon-associated proteins or TRAPs). In yeast it is a heterotrimeric complex consisting of Sec61p, Sbh1p, and Sss1p. The Sec61 complex functions in cotranslational and posttranslational translocation events.