Catalysis of the linkage of ubiquitin with lysine residues on a target protein. This function may be performed alone or in conjunction with E3, ubiquitin-protein ligase.

Catalysis of the reaction: ATP + ubiquitin + protein lysine = AMP + diphosphate + protein N-ubiquityllysine. Catalyzes the mediation of substrate recognition in ubiquitin-mediated protein degradation; binds directly to the substrate and its cognate E2 (ubiquitin conjugating enzyme).

Catalysis of the hydrolysis of various forms of polymeric ubiquitin sequences. Will remove ubiquitin from larger leaving groups.

Catalysis of the cleavage of the N-C1' glycosidic bond between the damaged DNA base and the deoxyribose sugar, releasing a free base and leaving an apyrimidinic (AP) site. Enzymes with this activity recognize and remove uracil bases in DNA that result from the deamination of cytosine or the misincorporation of dUTP opposite an adenine.

The physiological processes that allow an embryo or foetus to develop within the body of a female animal. It covers the time from fertilization of a female ovum by a male spermatozoon until birth.

Attachment of the fertilized egg to the uterine lining.

Catalysis of the reaction: urate + O2 + H2O = 5-hydroxyisourate + H2O2.

negative regulation of DNA recombination

Any process that stops, prevents or reduces the rate of DNA recombination.

The inherent decline over time, from the optimal fertility and viability of early maturity, that culminates in death and may be preceded by other indications, such as sterility.

The directed movement of monosaccharides into, out of, within or between cells. Monosaccharides are the simplest carbohydrates; they are polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms. They form the constitutional repeating units of oligo- and polysaccharides.

Progression of the cell from its inception to the end of its lifespan.

The formation from simpler components of cyclic AMP, adenosine 3',5'-phosphate.