Any process that modulates the frequency, rate or extent of Rac protein signal transduction.

A complex of four polypeptides, comprising large and small DNA polymerase alpha subunits and two primase subunits, which catalyzes the synthesis of an RNA primer on the lagging strand of replicating DNA; the smaller of the two primase subunits alone can catalyze oligoribonucleotide synthesis.

Catalysis of the reaction: ATP + deoxyribonucleotide(n) + deoxyribonucleotide(m) = AMP + diphosphate + deoxyribonucleotide(n+m).

A change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of exposure to acid.

A multimeric enzyme complex, which in humans is a heterotetramer of four subunits of approximately 125, 50, 68 and 12kDa. Also includes the delta DNA polymerase cofactor. Functions in DNA replication, mismatch repair and excision repair.

positive regulation of Rac protein signal transduction

Any process that activates or increases the frequency, rate or extent of Rac protein signal transduction.

Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).

regulation of Rho protein signal transduction

Any process that modulates the frequency, rate or extent of Rho protein signal transduction.

negative regulation of Rho protein signal transduction

Any process that stops, prevents or reduces the frequency, rate or extent of Rho protein signal transduction.

The process whereby relatively unspecialized cells acquire specialized structural and/or functional features of leading edge cells, cells at the front of a migrating epithelial sheet.

Catalysis of a topological transformation in double-stranded DNA by a covalent or non-covalent mechanism.

Catalysis of a DNA topological transformation by transiently cleaving one DNA strand at a time to allow passage of another strand; changes the linking number by +1 per catalytic cycle.

The chemical reactions involving RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage.