The process of removing one or more phosphoric (ester or anhydride) residues from a molecule.

Any specialized areas of the plasma membranes of adjacent cells where the membranes are 2-4 nm apart and penetrated by a connexon.

The progressive compaction of dispersed interphase chromatin into threadlike chromosomes prior to mitotic or meiotic nuclear division, or during apoptosis, in eukaryotic cells.

positive regulation of Ras protein signal transduction

Any process that activates or increases the rate of Ras protein signal transduction.

Catalysis of the removal of one of the two phosphate groups of an inositol bisphosphate.

An assembly of six molecules of connexin, made in the Golgi apparatus and subsequently transported to the plasma membrane, where docking of two connexons on apposed plasma membranes across the extracellular space forms a gap junction.

The morphological and physiological alterations undergone by the nucleus during apoptosis.

A belt-like region of very close contact between the plasma membranes of adjacent cells so that the intercellular space is completely occluded. They occur in epithelia and brain endothelia.

The process by which replicated homologous chromosomes are physically separated into two sets during the first division of meiosis. Each replicated chromosome, composed of two sister chromatids, aligns at the cell equator, paired with its homologous partner; this pairing off, referred to as synapsis, permits genetic recombination. One homolog (both sister chromatids) of each morphologic type goes into each of the resulting chromosome sets.

Catalysis of the reaction: phosphatidylinositol-3,4,5-trisphosphate + H2O = phosphatidyl inositol-4,5-bisphosphate + phosphate.

An adherens junction which connects a cell to the extracellular matrix.

The breakdown of the nucleus into small membrane-bounded compartments, or blebs, each of which contain compacted DNA.

Small region on the surface of a cell that anchors the cell to the extracellular matrix and that are points of termination of actin filaments.