Catalysis of the hydrolysis of peptide bonds in substrates containing five or more amino acids, preferentially with Ala in P1', and Pro in P2'.

endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters

Catalysis of the hydrolysis of ester linkages within nucleic acids by creating internal breaks to yield 3'-phosphomonoesters.

purine-specific oxidized base lesion DNA N-glycosylase activity

Catalysis of the removal of oxidized purine bases by cleaving the N-C1' glycosidic bond between the oxidized purine and the deoxyribose sugar. The reaction involves the formation of a covalent enzyme substrate intermediate. Release of the enzyme and free base by a beta-elimination or a beta, gamma-elimination mechanism results in the cleavage of the DNA backbone 3' of the apurinic (AP) site.

Stops, prevents or reduces the activity of the enzyme phospholipase A2.

The rupture of cell membranes and the loss of cytoplasm.

exoribonuclease activity, producing 5' phosphomonoesters

Catalysis of the hydrolysis of ester linkages within ribonucleic acids by removing nucleotide residues from the 3' or 5' end to yield 5' phosphomonoesters.

Interacting selectively with Ran, a conserved Ras-like GTP-binding protein, implicated in nucleocytoplasmic transport, cell cycle progression, spindle assembly, nuclear organization and nuclear envelope (NE) assembly.

A multisubunit complex that activates the hydrolysis of small nonubiquitinated peptides by binding to the proteasome core complex.

regulation of immune cell mediated cytotoxicity

regulation of immune cell mediated cell killing

Any process that modulates the frequency, rate, or extent of immune cell mediated cytotoxicity.

Catalysis of the activation of the proteasome, a large multisubunit complex which performs regulated ubiquitin-dependent cytosolic and nuclear proteolysis.

Interacting selectively with any growth factor, proteins or polypeptides that stimulate a cell or organism to grow or proliferate.

Separation of duplicated centrosome components at the beginning of mitosis. The centriole pair within each centrosome becomes part of a separate microtubule organizing center that nucleates a radial array of microtubules called an aster. The two asters move to opposite sides of the nucleus to form the two poles of the mitotic spindle.