Catalysis of the hydrolysis of peptide bonds. Specificity similar to, but narrower than, that of pepsin A. Does not cleave the Gln4-His5 bond in the B chain of insulin.

negative regulation of lymphocyte proliferation

Any process that stops, prevents or reduces the rate or extent of lymphocyte proliferation.

Catalysis of the hydrolysis of peptide bonds. Similar to cathepsin D, but slightly broader specificity.

The multiplication or reproduction of epithelial cells, resulting in the rapid expansion of a cell population. Epithelial cells make up the epithelium, the covering of internal and external surfaces of the body, including the lining of vessels and other small cavities. It consists of cells joined by small amounts of cementing substances.

Catalysis of the hydrolysis of peptide bonds. Preferential cleavage: hydrophobic, preferably aromatic, residues in P1 and P1' positions. Cleaves Phe1-Val2, Gln4-His5, Glu13-Ala14, Ala14-Leu15, Leu15-Tyr16, Tyr16-Leu17, Gly23-Phe24, Phe24-Phe25 and Phe25-Tyr26 bonds in the B chain of insulin.

Catalysis of the cleavage of Leu-Xaa bond in angiotensinogen to generate angiotensin I.

Catalysis of the reaction: gamma-aminobutyric acid(out) + H+(out) = gamma-aminobutyric acid(in) + H+(in).

Progression through the second phase of meiosis, in which cells divide and separate the two chromatids in each chromosome.

Progression through prophase of meiosis II; analogous to mitotic prophase.

Catalysis of the hydrolysis of nonterminal peptide linkages in oligopeptides or polypeptides; a cysteine residue is at the active center.

Catalysis of the preferential cleavage of Tyr-Xaa, Met-Xaa or Arg-Xaa with Leu or Val as the P2 residue.

regulation of epithelial cell proliferation

Any process that modulates the frequency, rate or extent of epithelial cell proliferation.

Catalysis of the reaction: Na+(out) + HCO3-(out) = Na+(in) + HCO3-(in).

The regulation of the levels, transport, and metabolism of hydrogen ions (protons) within a cell or between a cell and its external environment.