Formation of the spliceosome, a ribonucleoprotein apparatus that catalyzes nuclear mRNA splicing via transesterification reactions.

Catalysis of the reaction which results in unsaturation at C-7 in the B ring of sterols.

Interacting selectively with a steroid, any of a large group of substances that have in common a ring system based on 1,2-cyclopentanoperhydrophenanthrene.

Interacting selectively with vitamin D, a fat soluble vitamin that contributes to the maintenance of normal levels of calcium and phosphorus in the human bloodstream. Vitamin D is also known as calciferol and five different forms are known, including ergocalciferol and cholecalciferol.

Catalysis of the transfer of a hydroxyl group from 2-oxoglutarate to a prolyl residue in a protein.

Catalysis of the reaction: peptidyl-proline (omega=180) = peptidyl-proline (omega=0).

Catalysis of the reaction: peptidyl L-proline + 2-oxoglutarate + O2 = procollagen trans-4-hydroxy-L-proline + succinate + CO2.

Catalysis of the rearrangement of both intrachain and interchain disulfide bonds in proteins.

trans-Golgi network transport vesicle membrane

The membrane surrounding a vesicle transporting substances between the trans-Golgi network and other parts of the cell.

Interacting selectively with monomeric actin, also known as G-actin.

ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism

Catalysis of the reaction: ATP + H2O = ADP + phosphate, to directly drive the transport of ions across a membrane. The reaction is characterized by the transient formation of a high-energy aspartyl-phosphoryl-enzyme intermediate.

retrograde transport, Golgi to endoplasmic reticulum

The directed movement of substances from the Golgi back to the endoplasmic reticulum, mediated by COP I vesicles.

The directed movement of substances within the Golgi, mediated by small transport vesicles. These either fuse with the cis-Golgi or with each other to form the membrane stacks known as the cis-Golgi reticulum (network).

The directed movement of substances that are gaseous in normal living conditions into, out of, within or between cells.