The formation from simpler components of interleukin-4.

metabotropic glutamate, GABA-B-like receptor activity

The group of G-protein coupled receptors that are structurally/functionally related to the metabotropic glutamate receptors.

The rapid expansion of a T cell population by cell division. Follows T cell activation.

An array of microtubules emanating from a spindle pole MTOC that do not connect to kinetochores.

mitochondrial inner membrane protein import

The import of proteins into the mitochondria inner membrane. Inner membrane proteins are first imported into the matrix space where the matrix-targeting sequence is removed; how these proteins then are incorporated into the inner membrane is not known.

A change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the perception of an extracellular stimulus.

The array of microtubules and associated molecules that forms between opposite poles of a eukaryotic cell during mitosis or meiosis and serves to move the duplicated chromosomes apart.

The process whereby a relatively unspecialized immature germ cell acquires the specialized features of a mature female gamete.

An intracellular organelle, about 200 A in diameter, consisting of RNA and protein. It is the site of protein biosynthesis resulting from translation of messenger RNA (mRNA). It consists of two subunits, one large and one small, each containing only protein and RNA. Both the ribosome and its subunits are characterized by their sedimentation coefficients, expressed in Svedberg units (symbol: S). Hence, the prokaryotic ribosome (70S) comprises a large (50S) subunit and a small (30S) subunit, while the eukaryotic ribosome (80S) comprises a large (60S) subunit and a small (40S) subunit. Two sites on the ribosomal large subunit are involved in translation, namely the aminoacyl site (A site) and peptidyl site (P site). Ribosomes from prokaryotes, eukaryotes, mitochondria, and chloroplasts have characteristically distinct ribosomal proteins.