A membrane adaptor complex that links clathrin to a membrane.

Any process that modulates the frequency, rate or extent of isotype switching.

The process by which the anatomical structures of the inner ear are generated and organized. Morphogenesis pertains to the creation of form. The inner ear is the structure in vertebrates that contains the organs of balance and hearing. It consists of soft hollow sensory structures (the membranous labyrinth) containing fluid (endolymph) surrounded by fluid (perilymph) and encased in a bony cavity (the bony labyrinth). It consists of two chambers, the sacculus and utriculus, from which arise the cochlea and semicircular canals respectively.

Catalysis of the reaction: 3-hydroxy-2-methylpropanoate + NAD+ = 2-methyl-3-oxopropanoate + NADH + H+.

The coat found on coated pits and the coated vesicles derived from coated pits; comprises clathrin and the AP-2 adaptor complex.

The breakdown into simpler components of low-density lipoproteins, also known as beta lipoproteins, one of the classes of lipoproteins found in the bloodstream of animals, acting as a carrier for cholesterol and fats.

Catalysis of the transfer of a phosphate group, usually from ATP, to a fructose substrate molecule.

The formation from simpler components of cysteine, via the intermediate cystathione.

Any of the vesicles of the constitutive secretory pathway, which carry cargo from theendoplasmic reticulumR to the Golgi, between Golgi cisternae, and to destinations within or outside the cell.

The formation from simpler components of cysteine, 2-amino-3-mercaptopropanoic acid.

A vesicle that mediates transport from the endoplasmic reticulum to the Golgi complex.

Catalysis of the reaction: D-aspartate + H2O + O2 = oxaloacetate + NH3 + H2O2.

Small membrane-bounded organelle formed by pinching off of a coated region of membrane. Some coats are made of clathrin, whereas others are made from other proteins.

The process whose specific outcome is the progression of a tooth or teeth over time, from formation to the mature structure(s).