Folding of the microtubule constituent proteins alpha- and beta-tubulin into the native alpha-beta heterodimer.

Increases the activity of a molecular chaperone.

Partial folding of alpha- or beta-tubulin into a non-native folding intermediate, mediated by cytosolic chaperonin CCT.

Completion of folding of alpha- and beta-tubulin; takes place subsequent to chaperonin-mediated partial folding; mediated by a complex of folding cofactors.

Folding of the microtubule constituent protein beta-tubulin.

negative regulation of microtubule depolymerization

Any process that stops, prevents or reduces the rate of microtubule polymerization; prevention of depolymerization of a microtubule can result from binding by 'capping' at the plus end (e.g. by interaction with another cellular protein of structure) or by exposing microtubules to a stabilizing drug such as taxol.

The assembly of a filopodium, a very long microspike extended by the leading edge of a motile cell such as a crawling fibroblast or amoeba, or by the growth cone of a developing nerve cell axon.

Interacting selectively with hydroxyapatite, the calcium phosphate mineral of formula Ca10(PO4)6(OH)2 found both in rocks of nonorganic origin and as a component of bone and dentine.

Catalysis of the reaction: sarcosine + acceptor + H2O = glycine + formaldehyde + reduced acceptor.

The assembly and arrangement of the cytoplasm and its components.

Interacting selectively with pyridoxal 5' phosphate, 3-hydroxy-5-(hydroxymethyl)-2-methyl4-pyridine carboxaldehyde 5' phosphate, the biologically active form of vitamin B6.

The continuous turnover of bone matrix and mineral that involves first, an increase in resorption (osteoclastic activity) and later, reactive bone formation (osteoblastic activity). The process of bone remodeling takes place in the adult skeleton at discrete foci. The process ensures the mechanical integrity of the skeleton throughout life and plays an important role in calcium homeostasis. An imbalance in the regulation of bone resorption and bone formation results in many of the metabolic bone diseases, such as osteoporosis.