The directed movement of pyruvate into, out of, within or between cells.

Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). A DNA polymerase function with both polymerase and 3'-exonuclease activities; functions in DNA replication, mismatch repair and excision repair.

The directed movement of water (H2O) into, out of, within or between cells.

Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). Cannot initiate a chain de novo. Requires a primer, which may be DNA or RNA.

Stimulates the hydrolysis and exchange of adenyl nucleotides by other proteins.

Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). A DNA-directed DNA polymerase that functions during replication, to promote the extension of forks whose progression is stopped for any reason; a non-processive enzyme with no 3'-5' exonuclease activity; possesses deoxycytidyl transferase activity, incorporating deoxycytidyl opposite abasic sites. Functions during DNA repair and mutagenesis. Composed of two subunits.

The central region of a chromosome that includes the centromere and associated proteins.

The directed movement of dicarboxylic acids into, out of, within or between cells.

gamma DNA-directed DNA polymerase activity

Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). The DNA-directed DNA polymerase responsible for the replication of mitochondrial DNA.

A multisubunit complex that is located at the pericentric region of DNA and provides an attachment point for the spindle microtubules.

The directed movement of a neurotransmitter into, out of, within or between cells. Neurotransmitters are any chemical substance that is capable of transmitting (or inhibiting the transmission of) a nerve impulse from a neuron to another cell.

Catalysis of the synthesis of short RNA primers for the Okazaki fragments on both DNA template strands at the replication fork. A DNA-directed RNA polymerase that forms a complex with alpha DNA polymerase.