The process whose specific outcome is the progression of the primary sexual characteristics over time, from their formation to the mature structures. The primary sexual characteristics are the testes in males and the ovaries in females and they develop in response to sex hormone secretion.

Catalysis of the transfer of a methyl group to an acceptor molecule.

Invertebrate-specific cell-cell junctions which form a band around the apical borders of epithelial cells and attach to actin filaments.

The covalent or conformational alteration of one or more fatty acids in a lipid, resulting in a change in that lipid.

Covalent attachment of a glycosyl residue to a lipid molecule.

The formation from simpler components of sphinganine, D-erythro-2-amino-1,3-octadecanediol.

The formation from simpler components of ceramides, any N-acylated sphingoid.

The breakdown into simpler components of ceramides, any N-acetylated sphingoid.

The formation from simpler components of hypusine, N6-(4-amino-2-hydroxybutyl)-L-lysine.

The chemical reactions involving hypusine, N6-(4-amino-2-hydroxybutyl)-L-lysine.

The action of a molecule that contributes to the structural integrity of an epidermal cutaneous structure.

Used as a holding place for cellular components whose precise localization is, as yet, unknown, or has not been determined by GO (the latter is the major reason for nodes to have this parent); this term should not be used for annotation of gene products.

The chemical reactions involving sphingoids, any of a class of compounds comprising sphinganine and its homologues and stereoisomers, and derivatives of these compounds.

A complex containing a heterodimer of a catalytic subunit and a regulatory (adaptor) subunit of any phosphoinositide 3-kinase (PI3K).

The deposition of calcium phosphate in bone tissue.

Assembly or disassembly of actin filaments by the addition or removal of actin monomers from a filament.

Combining with estrogen to initiate a change in cell activity.

A allosteric homotetrameric molecule with glycolytic activity.