SRP-dependent cotranslational protein targeting to membrane, translocation

The process during cotranslational membrane targeting wherein proteins move across a membrane. SRP and its receptor initiate the transfer of the nascent chain across the endoplasmic reticulum (ER) membrane; they then dissociate from the chain, which is transferred to a set of transmembrane proteins, collectively called the translocon. Once the nascent chain translocon complex is assembled, the elongating chain passes directly from the large ribosomal subunit into the centers of the translocon, a protein-lined channel within the membrane. The growing chain is never exposed to the cytosol and does not fold until it reaches the ER lumen.

SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition

signal sequence recognition during SRP-dependent cotranslational protein targeting to membrane

The process by which SRP binds to the signal peptide in a nascent protein, causing protein elongation to pause, during cotranslational membrane targeting.

The chemical reactions involving triacylglycerol, any triester of glycerol. The three fatty acid residues may all be the same or differ in any permutation. Triacylglycerols are important components of plant oils, animal fats and animal plasma lipoproteins.

The chemical reactions involving membrane lipids, any lipid found in or associated with a biological membrane.

The chemical reactions involving phospholipids, any lipid containing phosphoric acid as a mono- or diester.

The formation from simpler components of phosphatidylethanolamine, any of a class of glycerophospholipids in which a phosphatidyl group is esterified to the hydroxyl group of ethanolamine.

The transfer of a phospholipid from its site of synthesis to the plasma membrane.

The chemical reactions involving fatty acids, aliphatic monocarboxylic acids liberated from naturally occurring fats and oils by hydrolysis.

The process by which the anatomical structures of cranial skeleton are generated and organized during the embryonic phase. Morphogenesis pertains to the creation of form.