Catalysis of the reaction: (R)-mevalonate + CoA + 2 NAD+ = 3-hydroxy-3-methylglutaryl-CoA + 2 NADH + 2 H+.

dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase activity

Catalysis of the addition of the second glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation; the transfer of glucose from dolichyl phosphate glucose (Dol-P-Glc) on to the lipid-linked oligosaccharide Glc(1)Man(9)GlcNAc(2)-PP-Dol.

Catalysis of the introduction of a trans double bond between C4 and C5 of the long chain base region of a sphingolipid. Sphingolipids are composed of a long chain base (LCB) amide-linked to a very long chain fatty acid.

Catalysis of the transfer of a xylosyl group to an acceptor molecule, typically another carbohydrate or a lipid.

Interacting selectively with major histocompatibility complex molecules; a set of molecules displayed on cell surfaces that are responsible for lymphocyte recognition and antigen presentation.

major histocompatibility complex class I ligand

Interacting selectively with major histocompatibility complex class I molecules; a set of molecules displayed on cell surfaces that are responsible for lymphocyte recognition and antigen presentation.

major histocompatibility complex class II ligand

protection from natural killer cell mediated cytotoxicity

protection from natural killer cell mediated cell killing

The process of protecting a cell from natural killer cell mediated cytotoxicity.

A complex of NXF1 and NXF2 required for the export of the majority of mRNAs from the nucleus to the cytoplasm; localized in the nucleoplasm and at both the nucleoplasmic and cytoplasmic faces of the nuclear pore complex; shuttles between the nucleus and the cytoplasm.

Enables the directed movement of proteins into, out of, within or between cells.

The formation of the constituents of the large ribosomal subunit and their export to the sites of protein synthesis.

The formation of the constituents of the small ribosomal subunit and their export to the sites of protein synthesis.