Catalysis of the reaction: L-tryptophan + tetrahydrobiopterin + O2 = 5-hydroxy-L-tryptophan + 4-alpha-hydroxytetrahydrobiopterin + H2O.

Any process that activates or increases the rate, frequency or extent of mitosis.

Catalysis of the reaction: L-tyrosine + tetrahydrobiopterin + O2 = 3,4-dihydroxy-L-phenylalanine + 4-alpha-hydroxytetrahydrobiopterin + H2O.

negative regulation of mitotic metaphase/anaphase transition

Any process that stops, prevents or reduces the rate, frequency or extent of the mitotic metaphase to anaphase transition.

Catalysis of the reaction: D-glucose 6-phosphate = 1D-myo-inositol 3-phosphate; requires NAD, which dehydrogenates the CHOH group to CO at C-5 of the glucose 6-phosphate, making C-6 into an active methylene, able to condense with the aldehyde at C-1. Finally, the enzyme-bound NADH reconverts C-5 into the CHOH form.

positive regulation of mitotic metaphase/anaphase transition

Any process that activates or increases the rate, frequency or extent of the mitotic metaphase to anaphase transition.

Catalysis of the reaction: CMP-N-acetylneuraminate + beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-beta-D-glucosylceramide = CMP + alpha-N-acetylneuraminyl-2,3-beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-D-glucosylceramide.

negative regulation of striated muscle development

Any process that stops, prevents or reduces the rate, frequency or extent of striated muscle development.

Catalysis of the reaction: nicotinate D-ribonucleotide + diphosphate + CO2 = pyridine-2,3-dicarboxylate + 5-phospho-alpha-D-ribose 1-diphosphate.

positive regulation of striated muscle development

Any process that activates or increases the rate, frequency or extent of striated muscle development.

Catalysis of the reaction: ATP + nicotinate ribonucleotide = diphosphate + deamido-NAD+.

regulation of natural killer cell activity

Any process that modulates the frequency, rate or extent of natural killer cell activity.

Catalysis of the reaction: nicotinate D-ribonucleotide + diphosphate = nicotinate + 5-phospho-alpha-D-ribose 1-diphosphate.