Catalysis of the release of an N-terminal amino acid, preferably a neutral or hydrophobic one, from a polypeptide. Aminoacyl-arylamides are poor substrates.

The region that lies just beneath the plasma membrane on the basal edge of a cell.

Catalysis of the hydrolysis of Xaa-Pro dipeptides; also acts on aminoacyl-hydroxyproline analogs. No action on Pro-Pro.

glutamate synthase activity, NADH or NADPH as acceptor

Catalysis of the reaction: 2 L-glutamate + NAD(P)+ = L-glutamine + 2-oxoglutarate + NAD(P)H + H+.

Catalysis of the hydrolysis of nonterminal peptide linkages in oligopeptides or polypeptides by a reaction mechanism involving a serine residue (and a histidine residue) at the active center of the enzyme.

Any substance involved in the initiation, activation, perpetuation, repression or termination of polypeptide synthesis at the ribosome.

Catalysis of the cleavage of the Leu-Leu bond in synthetic tetradecapeptide renin substrate, producing angiotensin I, but not active on natural angiotensinogen. Also hydrolyzes BZ-Arg-para-nitroanilide.

translation factor activity, non-nucleic acid binding

Any of a group of soluble proteins involved in polypeptide synthesis at the ribosome which do not bind to nucleic acids.

Catalysis of the reaction: acylaminoacyl-peptide + H2O = acylamino acid + peptide.

The directed movement of a protein to a specific location.

The processes by which a protein is maintained in a location and prevented from moving elsewhere. These include sequestration, stabilization to prevent transport elsewhere and the active retrieval of proteins that do move away.

Assembly of the zonula adherens, a cell-cell adherens junction which forms a continuous belt near the apex of epithelial cells.

regulation of circadian sleep/wake cycle, sleep

Any process that modulates the frequency, rate or extent of sleep; a readily reversible state of reduced awareness and metabolic activity that occurs periodically in many animals.

regulation of circadian sleep/wake cycle, non-REM sleep

Any process that modulates the frequency, rate or extent of non-rapid eye movement sleep.