Specialized membrane domains composed mainly of cholesterol and sphingolipids, and are relatively poor in polyunsaturated lipids such as glycerophospholipids. The formation of these membrane domains is promoted by the presence of cholesterol in the lipid bilayer: the rigid hexagonal rings of cholesterol can pack tightly against the saturated hydrocarbon chains of some membrane lipids, allowing these lipids to assemble into cohesive units floating in the mass of loosely packed polyunsaturated plasma membrane components.

The process of physically separating progeny cells during cytokinesis; this may involve enzymatic digestion of septum or cell wall components.

Assembly and organization of septins and associated proteins into a structure resembling a ring at the cell cortex.

The migration of immune cells (leukocytes) from the blood vessels into the surrounding tissue.

Either of the ends of a spindle, where spindle microtubules are organized; usually contains a microtubule organizing center and accessory molecules, spindle microtubules and astral microtubules.

Catalysis of the release of an N-terminal dipeptide, by the hydrolysis of the Xbb-Xcc bond in Xaa-Xbb-Xcc, preferentially when Xbb is Pro, provided Xcc is neither Pro nor hydroxyproline.

Any process that modulates the frequency, rate or extent of bone tissue loss (resorption).

Catalysis of the selective cleavage of Lys6-Ile7 bond in trypsinogen.

Catalysis of the release of mature proteins from their proproteins by cleavage of the terminal bond of Arg-Xaa-Yaa-Arg-Z motifs where Xaa can be any amino acid and Yaa is Arg or Lys. Releases albumin, complement component C3 and von Willebrand factor from their respective precursors.

Catalysis of the hydrolysis of proteins, including fibronectin, type IV collagen and nucleolin. Preferential cleavage: Arg-Xaa

Catalysis of the reaction: ATP + N-acetyl-D-glucosamine = ADP + N-acetyl-D-glucosamine 6-phosphate.

Catalysis of the preferential cleavage of Asp-Xaa

Catalysis of the removal of acetyl groups from histones, independently of NAD.