transmembrane receptor protein tyrosine kinase signaling pathway

transmembrane receptor protein tyrosine kinase signalling pathway

The series of molecular signals generated as a consequence of a transmembrane receptor tyrosine kinase binding to its physiological ligand.

spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)

Rearrangement of the pre-catalytic spliceosome containing U4 (or U4atac) and U1 (or U11) snRNPs to unpair U4 (or U4atac) from U6 (or U6atac) and release it from the spliceosomal complex along with U1 (or U11).

The contractile ring formed by a dividing cell. As in, but not restricted to, the fungi (Fungi, ncbi_taxonomy_id:4751).

A ring-shaped structure that forms at the site of cytokinesis in fungal cells; composed of the conserved family of filament forming proteins called septins as well as septin-associated proteins. As in, but not restricted to, the fungi (Fungi, ncbi_taxonomy_id:4751).

U2-type nuclear mRNA branch site recognition

Recognition of the intron branch site sequence of a U2-type intron. This recognition may include an interaction between the U2 snRNA (as part of the U2 snRNP) and the branch site sequence of the pre-mRNA. In cis-splicing, the U1 snRNP, already associated with the 5'-splice site may also be involved in recruiting the U2 snRNP to the branch site.

A long bundle of actin filaments, comprising filamentous actin and associated proteins, found in cells.

The splicing of Group I introns. This occurs by a ribozymic mechanism where the intron sequence forms a distinct 3D structure, characteristic of Group I introns and involved in determining the locations of the splice sites (there do not appear to be consensus splice site sequences) as well as having a role in catalyzing the splicing reactions, though protein factors are also required in vivo. Splicing occurs by a series of two transesterification reactions, generally with exogenous guanosine as the initiating nucleophile. The intron is excised as a linear piece (though it may subsequently circularize).