The formation from simpler components of 3'-phosphoadenosine 5'-phosphosulfate, a naturally occurring mixed anhydride. It is an intermediate in the formation of a variety of sulfo compounds in biological systems.

Catalysis of the preferential cleavage: Phe-Xaa

RNA polymerase I transcription factor complex

A transcription factor complex that acts at promoters of genes transcribed by RNA polymerase I.

Catalysis of the reaction: ATP + 5-formyltetrahydrofolate = ADP + phosphate + 5,10-methenyltetrahydrofolate.

Catalysis of the reaction: glycerol 1-phosphate + H2O = glycerol + phosphate.

Combining with the cyclic peptide hormone melanin-concentrating hormone to initiate a change in cell activity.

negative regulation of transcription from RNA polymerase II promoter

negative regulation of transcription from Pol II promoter

Any process that stops, prevents or reduces the rate, frequency or extent of transcription from an RNA polymerase II promoter.

Interacting selectively with a LIM domain (for Lin-11 Isl-1 Mec-3) of a protein, a domain with seven conserved cysteine residues and a histidine, that binds two zinc ions and acts as an interface for protein-protein interactions.

Complex that possesses histone acetyltransferase activity.

Interacting selectively with a LRR domain (leucine rich repeats) of a protein.

A large multiprotein complex that possesses histone acetyltransferase and in involved in regulation of transcription. The budding yeast complex includes Gcn5p, several proteins of the Spt and Ada families, and several TBP-associate proteins (TAFs); analogous complexes in other species have analogous compositions, and usually contain homologs of the yeast proteins.

Interacting selectively with clathrin, a 180 kDa protein that is the main component of the coat of coated vesicles and coated pits, and which also occurs in synaptic vesicles.

A large multiprotein complex that possesses histone acetyltransferase and is involved in regulation of transcription. The composition is similar to that of the SAGA complex, but includes fewer Spt and Ada proteins, and more TAFs.