muscarinic acetylcholine receptor, adenylate cyclase inhibiting pathway

muscarinic acetylcholine receptor, adenylyl cyclase inhibiting pathway

The series of molecular signals generated as a consequence of a muscarinic acetylcholine receptor binding to its physiological ligand, followed by inhibition of adenylyl cyclase and a subsequent decrease in the concentration of cyclic AMP.

serotonin receptor, adenylate cyclase inhibiting pathway

The series of molecular signals generated as a consequence of a serotonin receptor binding to its physiological ligand, followed by inhibition of adenylyl cyclase and a subsequent decrease in the concentration of cyclic AMP.

G-protein signaling, coupled to cGMP nucleotide second messenger

G-protein signalling, coupled to cGMP nucleotide second messenger

The series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand, followed by activation of guanylyl cyclase and a subsequent increase in the concentration of cyclic GMP.

A heterodimeric complex involved in the release of a nascent polypeptide chain from a ribosome.

cis assembly of U2-type pre-catalytic spliceosome

Assembly of a U2-type spliceosomal complex containing the intact pre-mRNA and all of the spliceosomal snRNPs. This occurs when the U4-U6/U5 tri-snRNP associates with the pre-mRNA and associated snRNPs in an ATP-dependent manner.

formation of catalytic spliceosome for second transesterification step

Conformational rearrangement of the spliceosomal complex containing the RNA products from the 1st step of splicing to form the catalytic site for the second step of splicing.

assembly of spliceosomal tri-snRNP U4/U6.U5

The formation of a tri-snRNP complex containing the U4, U6, and U5 snRNAs and associated proteins. This includes reannealing of U4 and U6 snRNAs released from previous rounds of splicing to reform the U4/U6 snRNP as well as the subsequent association of the U5 snRNP with the U4/U6 snRNP to form the tri-snRNP that is ready to reassemble into another U2-type spliceosome complex.