The formation from simpler components of a glycosylphosphatidylinositol (GPI) anchor that attaches some membrane proteins to the lipid bilayer of the cell membrane. The phosphatidylinositol moiety is linked via the C-6 hydroxyl residue of inositol to a carbohydrate chain which is itself linked to the protein via an ethanolamine phosphate moiety, its amino group forming an amide linkage with the C-terminal carboxyl of the protein. Some GPI anchors have variants on this canonical linkage.

The formation of the neural tube from an epithelial cell sheet (the neuroepithelium or neural plate). In primary neurulation, the neural plate cells surrounding the neural plate direct the neural plate cells to proliferate, invaginate, and pich off from the surface to form a hollow epithelial tube. Primary neurulation is the typical mechanism of formation of the anterior neural tube.

The hydrolysis of a peptide bond or bonds within a protein.

The proteolytic cleavage of transmembrane proteins and release of their ectodomain (extracellular domain).

Any process that modulates the frequency, rate or extent of gliogenesis, the formation of mature glia.

Any process that stops, prevents or reduces the rate, frequency or extent of gliogenesis, the formation of mature glia.

Any process that activates or increases the rate, frequency or extent of gliogenesis, the formation of mature glia.

The process whereby a relatively unspecialized cell acquires specialized features of a neuroblast. There are at least four stages through which the pluripotent cells of epiblast or blastula become neuroblasts.

The process whereby the developmental fate of a cell becomes restricted such that it will differentiate into a neuroblast.

The chemical reactions involving icosanoids, any of a group of C20 polyunsaturated fatty acids.

The chemical reactions involving leukotriene, a pharmacologically active substance derived from a polyunsaturated fatty acid, such as arachidonic acid.

The chemical reactions involving prostanoids, any compound based on or derived from the prostanoate structure.