A multi subunit protease complex located in the endoplasmic reticulum membrane that cleaves the signal sequence from precursor proteins following their transport out of the cytoplasmic space.

The formation from simpler components of macromolecules, large molecules including proteins, nucleic acids and carbohydrates.

The volume enclosed by the membranes of the endoplasmic reticulum.

The lipid bilayer surrounding the endoplasmic reticulum.

branched chain family amino acid metabolism

The chemical reactions involving amino acids containing a branched carbon skeleton, comprising isoleucine, leucine and valine.

A prelysosomal endocytic organelle defined by the time it takes for endocytosed macromolecules to be delivered. The time of delivery may vary ; for example, late endosomes are usually loaded 4-30 min after endocytic uptake in mammalian cells. late endosomes are more spherical than early endosomes and are mostly juxtanuclear, being concentrated near the microtubule organizing center. They are differentiated from early endosomes by their lower lumenal pH and different protein composition.

branched chain family amino acid biosynthesis

branched chain family amino acid synthesis

The formation from simpler components of amino acids containing a branched carbon skeleton, comprising isoleucine, leucine and valine.

A type of late endosome in which regions of the limiting endosomal membrane invaginate to form internal vesicles; membrane proteins that enter the internal vesicles are sequestered from the cytoplasm.

branched chain family amino acid catabolism

branched chain family amino acid degradation

The breakdown into simpler components of amino acids containing a branched carbon skeleton, comprising isoleucine, leucine and valine.

glutamine family amino acid biosynthesis

The formation from simpler components of amino acids of the glutamine family, comprising arginine, glutamate, glutamine and proline.

A closed structure, found only in eukaryotic cells, that is completely surrounded by unit membrane and contains liquid material.