The clearance of liquid from the epithelial tubes of the insect tracheal system, shortly before the emergence of the larva, to generate an air-filled tubule system.

The most apical region of the lateral plasma membrane of an invertebrate epithelial cell. The subapical complex lies above the zonula adherens and the septate junction, and is comparable to the position of the tight junction of vertebrate cells.

Catalysis of the addition of a phosphate group to an inositol lipid at the 3' position of the inositol ring to generate the 3-phosphoinositides: phosphatidylinositol-3-phosphate [PI(3)P], phosphatidylinositol-3,4-bisphosphate [PI(3,4)P2] and phosphatidylinositol-3,4,5-trisphosphate [PI(3,4,5)P3].

The formation of a protein tetramer, a macromolecular structure consisting of four noncovalently associated nonidentical subunits.

phosphatidylinositol 3-kinase, class I, catalyst activity

Catalysis of the reaction: ATP + 1-phosphatidyl-1D-myo-inositol 4-phosphate = ADP + 1-phosphatidyl-1D-myo-inositol 3,4-bisphosphate.

The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of nonidentical component monomers. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer.

The blackening of the wounded area of the cuticle or the surface of invading pathogens, parasites or parasitoids, resulting from a proteolytic cascade leading to the de novo synthesis and deposition of melanin.

regulation of melanization defense response

regulation of melanization defence response

Any process that affects the rate, extent or location of the melanization defense response during injury or invasion.

The directed movement of the spindle to a specific location in the cell.

The processes that set the alignment of spindle relative to other cellular structures.

negative regulation of melanization defense response

negative regulation of melanization defence response

Any process that reduces the rate or extent of the melanization defense response. This regulation is critical to limit melanization to the site of injury or infection.