Interacting selectively with inositol 1,3,4,5 tetrakisphosphate.

Partitioning the posterior region of the head anlage into gnathal (mandibular, maxillary and labial) segments. Unlike the anterior head (procephalic) segments, formation of the posterior head (gnathal) segments occurs by a similar mechanism to trunk segmentation, where a cascade of gap genes, pair-rule genes and segment-polarity genes subdivide the embryo into progressively smaller domains.

The orderly movement of endothelial cells into the extracellular matrix in order to form new blood vessels during angiogenesis.

Interacting selectively with an integrin.

regulation of blood vessel endothelial cell migration

Any process that modulates the frequency, rate or extent of the migration of the endothelial cells of blood vessels.

The action characteristic of a hormone, any substance formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells in the same organism, upon which it has a specific regulatory action. The term was originally applied to agents with a stimulatory physiological action in vertebrate animals (as opposed to a chalone, which has a depressant action). Usage is now extended to regulatory compounds in lower animals and plants, and to synthetic substances having comparable effects.

positive regulation of blood vessel endothelial cell migration

Any process that activates or increases the rate, frequency or extent of the migration of the endothelial cells of blood vessels.

negative regulation of blood vessel endothelial cell migration

Any process that stops, prevents or reduces the rate, frequency or extent of the migration of the endothelial cells of blood vessels.

protein serine/threonine kinase activator activity

protein ser/thr kinase activator activity

Increases the activity of a protein serine/threonine kinase.

Progression of the endocrine system over time, from its formation to a mature structure. The endocrine system is a system of hormones and ductless glands, where the glands release hormones directly into the blood, lymph or other intercellular fluid, and the hormones circulate within the body to affect distant organs. The major glands that make up the human endocrine system are the hypothalamus, pituitary, thyroid, parathryoids, adrenals, pineal body, and the reproductive glands which include the ovaries and testes.