Combining with the corticotrophin-releasing factor family of ligands, including the urocortins, to initiate a change in cell activity.

Combining with thrombin to initiate a change in cell activity.

epidermal growth factor-like module containing hormone receptor activity

Catalysis of the reaction: 5-methyltetrahydrofolate + L-homocysteine = tetrahydrofolate + L-methionine.

Enables the directed movement of sodium ions (Na+) into, out of, within or between cells.

di-, tri-valent inorganic cation transporter activity

Enables the directed movement of inorganic cations with a valency of two or three into, out of, within or between cells. Inorganic cations are atoms or small molecules with a positive charge which do not contain carbon in covalent linkage.

Catalysis of the reaction: 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholanate + NAD+ = 3-alpha,12-alpha-dihydroxy-7-oxo-5-beta-cholanate + NADH + H+.

Enables the directed movement of calcium (Ca) ions into, out of, within or between cells.

Enables the directed movement of cadmium (Cd) ions into, out of, within or between cells.

Enables the directed movement of cobalt (Co) ions into, out of, within or between cells.

Catalysis of the reaction: Cu+(out) = Cu+(in).

The process by which a segment of DNA is incorporated into another, usually larger, DNA molecule such as a chromosome.

Enables the directed movement of charged atoms or small charged molecules into, out of, within or between cells.

monovalent inorganic cation transporter activity

Enables the directed movement of inorganic cations with a valency of one into, out of, within or between cells. Inorganic cations are atoms or small molecules with a positive charge which do not contain carbon in covalent linkage.

Enables the directed movement of hydrogen ions into, out of, within or between cells.

Enables the directed movement of potassium ions (K+) into, out of, within or between cells.

Catalysis of the reaction: UDP-glucuronate + acceptor = UDP + acceptor beta-D-glucuronoside.

Combining with an extracellular or intracellular messenger, and in cooperation with a nearby primary receptor, initiating a change in cell activity.