Catalysis of the reaction: ATP + H2O = ADP + phosphate. Catalysis of the severing of a microtubule at a specific spot along its length, coupled to the hydrolysis of ATP.

The conversion of DNA-damage induced single-stranded gaps into large molecular weight DNA after replication, without removing the replication-blocking lesions, and with an increase in the endogenous mutation level. For example, in E. coli, a low fidelity DNA polymerase, pol V, copies lesions that block replication fork progress. This produces mutations specifically targeted to DNA template damage sites, but it can also produce mutations at undamaged sites.

Catalysis of movement along a microtubule toward the minus end, coupled to the hydrolysis of ATP (or GTP).

Interacting selectively with peptides, any of a group of organic compounds comprising two or more amino acids linked by peptide bonds.

The chemical reactions involving one of a family of organic molecules consisting of a purine base covalently bonded to a sugar ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside).

A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cocaine stimulus. Cocaine is a crystalline alkaloid obtained from the leaves of the coca plant.

hydrogen-exporting ATPase activity, phosphorylative mechanism

Catalysis of the reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out); by a phosphorylative mechanism.

A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus.

sodium-exporting ATPase activity, phosphorylative mechanism

sodium exporting ATPase activity, phosphorylative mechanism

Catalysis of the reaction: ATP + H2O + Na+(in) = ADP + phosphate + Na+(out); by a phosphorylative mechanism.

The formation from simpler components of interleukin-1, an interleukin produced mainly by activated macrophages. It is involved in the inflammatory response, and is identified as an endogenous pyrogen.