calcTNullFast {sigPathway}R Documentation

Compute Null T Distribution for Each Gene

Description

Computes a null t distribution for each gene by permuting the phenotypes.

Usage

calcTNullFast(tab, phenotype, nsim, ngroups = 2)

Arguments

tab a numeric matrix of expression values, with the rows and columns representing probe sets and sample arrays, respectively
phenotype a numeric vector indicating the phenotype
nsim an integer indicating the number of permutations to use
ngroups an integer indicating the number of groups in the expression matrix

Details

Similar to calcTStatFast but calculates t-statistics over permuted phenotypes. Please refer to the help file of calcTStatFast for more details.

Value

A matrix with nsim rows and nrow(tab) columns.

Author(s)

Weil Lai


[Package sigPathway version 1.1-3 Index]