This page contains a detailed annotation of mouse specific gene sets for agonists, antagonists, receptors, signal transduction components, and nuclear components encompassing the five known signaling pathways that are required for tooth development to reach E14.5 cap-stage: Wnt/Ctnnb1, Bmp, Fgf, Hedgehog (Hh), and Activin. Each gene is assigned to have either an activating or an inhibiting effect on the overall pathway activity. Each entry in our pathway annotation is supported by at least one primary research reference.

View Signaling Information

  • Wnt Pathway

  • Bmp Pathway

  • Fgf Pathway

  • Hh Pathway

  • Activin Pathway

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