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Welcome!

We are a bioinformatics research group and are part of the Center for Biomedical Informatics at Harvard Medical School, Children's Hospital Informatics Program, Harvard-MIT Division of Health, Science, & Technology, and the Partners Center for Personalized Genetic Medicine.

We are located at two places: Countway Library of Medicine and the HMS New Research Building.

News:

* Congratulations to Michael Tolstorukov! His paper on nucleosome organization was featured on the cover of Genome Research in June, 2009. See the picture on the right.


Introduction

Recent technological developments have enabled researchers to generate experimental data in an unprecedented, genome-wide scale. Our aim is to gain biological insights through computational and statistical analysis of genomic data.

Integrative analysis of genomic data

Methodological work: We develop new statistical and computational algorithms and tools for understanding a variety of genomic data, with a focus on methods for next-generation sequencing. Our goal is to address important problems and come up with efficient and statistically valid methods that will have practical impact on biological and clinical investigators.

Collaborative work: We work closely with several basic and clinical research groups. We strive to maintain a close and synergistic relationship through which we can address important biological and methdological problems effectively.

 

See the latest flyer for postdoctoral fellowship announcement!

Open Positions (August, 2009):

We are always recruiting new members!

NOTE: Please read the instructions on what to send. If you do not send the requested items, you will not receive a reply. Please note '[POSTDOC]' or '[GRAD]' in the subject line. If you do not hear back in one week, feel to send a reminder.

Postdoctoral Fellowship:

Multiple post-doctoral fellowships in bioinformatics are available immediately to work in the laboratory of Dr. Peter Park at Harvard Medical School.

The long-term goal of the group is to understand gene regulation through computational analysis of genomic data, with focus on epigenetic aspects. Positions: i) statistical methods for combining multiple genomics data types; ii) cancer genomics, combining data from expression, copy number, miRNA, SNP, methylation, and mutation sequencing; iii) chromatin structure and function using ChIP-seq data; iv) systems biology of organ regeneration, involving analysis of expression data and pathways. In each position, the successful candidate will have an opportunity to work on fantastic new data sets using the latest technologies including Illumina/SOLiD sequencing.

Ideal candidates will have a Ph.D. in a quantitative field and a substantial experience in analysis of genomic data. Excellent programming skills are essential and previous experience with R is a plus. Those who have applied previously are welcomed to apply again. The Harvard Medical area is one of the most exciting places in the world for biomedical research and our collaborators are among the top biologists.

Please send your CV, a brief statement of research interests, pdfs of your three best papers, and three letters of recommendations to peter_park@harvard.edu

Graduate Students

There are multiple openings for graduate students to work on the problems described above. The focus of the work will be computational; but, if desired, the student will have ample opportunity to carry out wet-lab work in one of the collaborating laboratories. Those with interest in epigenetics are particularly welcomed. NOTE: The student must already be enrolled in a graduate program at Harvard (Biophysics, Biological and Biomedical Sciences, or others) or at MIT (Health Sciences & Technology or others). Inquires regarding graduate student positions from those not already enrolled in one of these programs will go unanswered.

Undergraduate Research Assistants (MIT UROP or Harvard):

Multiple positions are open for undergraduates throughout the year. A 10-hour commitment during the term and full-time commitment during summer are required. Strong quantitative background and substantial programming experience are essential. Underclassmen with such experience are welcome to apply. You may also be interested in the Summer Institute in Bioinformatics and Integrative Genomics at Harvard-MIT Health, Science and Technology.