Recombination occurring within or between DNA molecules in somatic cells.

The mechanisms by means of which sequence diversity of antibodies is generated.

Catalysis of the reaction: acyl-CoA + NADP+ = trans-2,3-dehydroacyl-CoA + NADPH + H+.

Mutations that result in amino acid changes in the rearranged V regions of antibodies occurring somatically, during the affinity maturation of B cells as they migrate into the germinal centers.

Interacting selectively with a sequence of uracil residues in an RNA molecule.

receptor signaling protein tyrosine kinase signaling protein activity

receptor signalling protein tyrosine kinase signalling protein activity

Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). A DNA-directed DNA polymerase that may be specific to lymphoid cells and play a role in the somatic hypermutation of antibody genes.

Any of the heteromeric enzymes that act in the TCA cycle.

JAK pathway signal transduction adaptor activity

A multisubunit protein complex in the endoplasmic reticulum membrane of eukaryotes that transfers lipid-linked oligosaccharide precursor to asparagine residues on nascent proteins; includes at least nine different subunits, at least in yeast.

Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to an adenine residue in an rRNA molecule.

Catalysis of the reaction: a 5'-ribonucleotide + H2O = a ribonucleoside + phosphate.

Any process that modulates the frequency, rate or extent of the covalent alteration of a histone.

negative regulation of histone modification

Any process that stops, prevents or reduces the frequency, rate or extent of the covalent alteration of a histone.

negative regulation of thymidylate synthase biosynthesis

Any process that stops, prevents or reduces the rate of the formation from simpler components of the enzyme thymidylate synthase.

regulation of alpha-beta T cell proliferation

regulation of alpha-beta T-lymphocyte proliferation

Any process that modulates the frequency, rate or extent of alpha-beta T cell proliferation.