Catalysis of the carrier-mediated transfer of one or more substances across a membrane. Transport occurs in three ways: uniport, a single species is transported by facilitated diffusion in a process not coupled to the utilization of a primary source of energy; antiport, two or more species are transported in opposite directions in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy; and symport, two or more species are transported together in the same direction in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy.

The directed movement of a cofactor into, out of, within or between cells. A cofactor is a substance that is required for the activity of an enzyme or other protein.

Catalysis of the reaction: (S)-3-hydroxyacyl-CoA + NAD+ = 3-oxoacyl-CoA + NADH + H+.

Catalysis of the reaction: NADPH + H+ + oxidized thioredoxin = NADP+ + reduced thioredoxin.

A transporter of solutes that utilizes a carrier-mediated process to catalyze uniport, symport or antiport between aqueous phases on either side of a lipid membrane.

Catalysis of the reaction: thiosulfate + cyanide = SO3(2-) (sulfite) + thiocyanate.

Enables the directed movement of vitamins into, out of, within or between cells. A vitamin is one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body.

Catalyze the transport of two or more molecular species across a membrane, transport being in the same direction.

Enables the directed movement of a cofactor into, out of, within or between cells. A cofactor is a substance that is required for the activity of an enzyme or other protein.

Catalysis of the reaction: solute(out) + cation(out) = solute(in) + cation(in).

Catalysis of the reaction: O-phospho-L-homoserine + H2O = L-threonine + phosphate.

Catalysis of the reaction: solute(out) + H+(out) = solute(in) + H+(in).

The chemical reactions of a cofactor, a substance that is required for the activity of an enzyme or other protein. Cofactors may be inorganic, such as the metal atoms zinc, iron, and copper in certain forms, or organic, in which case they are referred to as coenzymes. Cofactors may either be bound tightly to active sites or bind loosely with the substrate.