Catalysis of the reaction: orotidine 5'-phosphate = UMP + CO2.

Catalysis of the reaction: 2-oxoglutarate + lipoamide = S-succinyldihydrolipoamide + CO2.

The directed movement of a drug, a substance used in the diagnosis, treatment or prevention of a disease, into, out of, within or between cells.

Catalysis of the reaction: ATP + pantothenate = ADP + D-4'-phosphopantothenate.

Catalysis of the reaction: ATP + pantetheine 4'-phosphate = diphosphate + dephospho-CoA.

Catalysis of the reaction: peptide L-aspartate + 2-oxoglutarate + O2 = peptide 3-hydroxy-L-aspartate + succinate + CO2.

The formation from simpler components of a pyrimidine ribonucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a ribose sugar) esterified with a phosphate moiety at either the 3' or 5'-hydroxyl group of its glycose moiety.

tricarboxylic acid cycle intermediate metabolism

citric acid cycle intermediate metabolism

The chemical reactions involving intermediates of the tricarboxylic acid cycle.

Any process that modulates the occurrence or rate of cell death by apoptosis.

The formation from simpler components of a pyrimidine deoxyribonucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a deoxyribose sugar) esterified with a phosphate moiety at either the 3' or 5'-hydroxyl group of its glycose moiety.

The chemical reactions involving citrate, 2-hydroxy-1,2,3-propanetricarboyxlate. Citrate is widely distributed in nature and is an important intermediate in the TCA cycle and the glyoxylate cycle.

The chemical reactions involving amyloid precursor protein (APP), the precursor of beta-amyloid, a glycoprotein associated with Alzheimer's disease.

The breakdown into simpler components of a pyrimidine ribonucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a ribose sugar) esterified with a phosphate moiety at either the 3' or 5'-hydroxyl group of its glycose moiety.

The chemical reactions involving isocitrate, the anion of isocitric acid, 1-hydroxy-1,2,3-propanetricarboxylic acid. Isocitrate is an important intermediate in the TCA cycle and the glycoxylate cycle.