Interacting selectively and simultaneously with one or more signal transduction molecules, usually acting as a scaffold to bring these molecules into close proximity either using their own SH2/SH3 domains (e.g.Grb2) or those of their target molecules (e.g. SAM68).

A change in state or activity of an organism (in terms of movement, secretion, gene expression, enzyme production, etc.) in response to temperatures above the optimal temperature for that organism.

synaptic vesicle membrane organization and biogenesis

The assembly and arrangement of the membrane surrounding a synaptic vesicle.

negative regulation of protein kinase activity

Any process that stops, prevents or reduces the rate of protein kinase activity.

Catalysis of the reaction: a phosphoprotein + H2O = a protein + phosphate. Together with protein kinases, these enzymes control the state of phosphorylation of cell proteins and thereby provide an important mechanism for regulating cellular activity.

transmembrane receptor protein serine/threonine kinase signaling protein activity

transmembrane receptor protein serine/threonine kinase signalling protein activity

A change in state or activity of an organism (in terms of movement, secretion, gene expression, enzyme production, etc.) in response to temperatures below the optimal temperature for that organism.

Catalysis of the reaction: protein serine/threonine phosphate + H2O = protein serine/threonine + phosphate.

Enables the directed movement of serotonin into, out of, within or between cells. Serotonin (5-hydroxytryptamine) is a monoamine neurotransmitter occurring in the peripheral and central nervous systems.

transforming growth factor beta receptor, cytoplasmic mediator activity

TGFbeta receptor, cytoplasmic mediator activity

Activity of any of the molecules that transmit the signal from a TGFbeta receptor through the cytoplasm to the nucleus.

calcium-dependent protein serine/threonine phosphatase activity

Catalysis of the reaction: protein tyrosine phosphate + H2O = protein tyrosine + phosphate.