The process whereby a relatively unspecialized cell acquires specialized features of a myoblast. A myoblast is a cell type that gives rise to mature contractile cells called myocytes. Fusion of myoblasts gives rise to the myotubes that eventually develop into skeletal muscle fibers.

Interacting selectively with a PDZ domain of a protein, a domain found in diverse signaling proteins.

The process whereby a relatively unspecialized cell acquires specialized features of an endothelial cell, a thin flattened cell. A layer of such cells lines the inside surfaces of body cavities, blood vessels, and lymph vessels, making up the endothelium.

The formation from simpler components of proteoglycans, any glycoprotein in which the carbohydrate units are glycosaminoglycans.

The alignment of chromosomes at the metaphase plate, a plane halfway between the poles of the mitotic spindle, during mitosis.

A series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue. These events include shape change, adhesiveness, aggregation, and release reactions. When carried through to completion, these events lead to the formation of a stable hemostatic plug.

Any process that modulates the frequency, rate or extent of the synthesis of either RNA on a template of DNA or DNA on a template of RNA.

Interacting selectively with low-density lipoprotein, one of the classes of lipoproteins found in blood plasma in many animals (data normally relate to humans).

Any process that modulates the frequency, rate or extent of the directed movement of substances between the nucleus and the cytoplasm.

negative regulation of nucleocytoplasmic transport

Any process that stops, prevents or reduces the rate of the directed movement of substances between the cytoplasm and the nucleus.

positive regulation of nucleocytoplasmic transport

Any process that activates or increases the rate of the directed movement of substances between the nucleus and the cytoplasm.

Any of the processes involved in the maintenance of an internal equilibrium within a defined tissue of an organism, including control of cellular proliferation and death and control of metabolic function.