The formation from simpler components of a glycosylphosphatidylinositol (GPI) anchor that attaches some membrane proteins to the lipid bilayer of the cell membrane. The phosphatidylinositol moiety is linked via the C-6 hydroxyl residue of inositol to a carbohydrate chain which is itself linked to the protein via an ethanolamine phosphate moiety, its amino group forming an amide linkage with the C-terminal carboxyl of the protein. Some GPI anchors have variants on this canonical linkage.

A change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the perception of an abiotic (non-living) stimulus.

Destruction of a protein or peptide by hydrolysis of peptide bonds.

Enables the directed movement of L-histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid, into, out of, within or between cells.

The proteolytic cleavage of transmembrane proteins and release of their ectodomain (extracellular domain).

Catalysis of the reaction: NAD+ + 4-trimethylammoniobutanal = NADH + 4-trimethylammoniobutanoate.

A change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of damage to the organism.

A change in state or activity of the organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the perception of a mechanical stimulus.

A change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the perception of a pest, a pathogen or a parasite.

A change in state or activity of the organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the perception of a virus.

A change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the perception of bacteria.

A change in state or activity of the organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the perception of a pathogenic (disease-causing) bacteria.