The terminal region of a linear chromosome that includes the telomeric DNA repeats and associated proteins.

The directed movement of tricarboxylic acids into, out of, within or between cells.

The directed movement of citrate, 2-hydroxy-1,2,3-propanetricarboyxlate, into, out of or within a mitochondrion.

The terminal region of a linear chromosome in the nucleus that includes the telomeric DNA repeats and associated proteins.

The ordered and organized complex of DNA and protein that forms the chromosome.

A complex comprised of DNA wound around a multisubunit core and associated proteins, which forms the primary packing unit of DNA into higher order structures.

The union of gametes of opposite sexes during the process of sexual reproduction to form a zygote. It involves the fusion of the gametic nuclei (karyogamy) and cytoplasm (plasmogamy).

The directed movement of pyruvate into, out of, within or between cells.

Catalysis of the reaction: phosphate + N-acylneuraminate 9-phosphate = H2O + phosphoenolpyruvate + N-acyl-D-mannosamine 6-phosphate.

Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). A DNA polymerase function with both polymerase and 3'-exonuclease activities; functions in DNA replication, mismatch repair and excision repair.

The directed movement of water (H2O) into, out of, within or between cells.

Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). Cannot initiate a chain de novo. Requires a primer, which may be DNA or RNA.

Stimulates the hydrolysis and exchange of adenyl nucleotides by other proteins.

Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). A DNA-directed DNA polymerase that functions during replication, to promote the extension of forks whose progression is stopped for any reason; a non-processive enzyme with no 3'-5' exonuclease activity; possesses deoxycytidyl transferase activity, incorporating deoxycytidyl opposite abasic sites. Functions during DNA repair and mutagenesis. Composed of two subunits.