A channel in a cell membrane whose opening is governed by the membrane potential.

Allows movement of calcium across a cell membrane through a transmembrane channel whose opening and closing is responsive to changes in membrane potential.

retention of protein in endoplasmic reticulum

The retention in the endoplasmic reticulum (ER) lumen of soluble resident proteins. Sorting receptors retrieve proteins with ER localization signals, such as KDEL and HDEL sequences or some transmembrane domains, that have escaped to the cis-Golgi network and return them to the ER. Abnormally folded proteins and unassembled subunits are also selectively retained in the ER.

The process of directing proteins towards the lysosome using signals contained within the protein.

The process of directing proteins towards the vacuole using signals contained within the protein.

regulation of transforming growth factor beta receptor signaling pathway

regulation of transforming growth factor beta receptor signalling pathway

Any process that modulates the frequency, rate or extent of activity of any TGFbeta receptor signaling pathway.

The process of directing proteins towards the peroxisome using signals contained within the protein.

Interacting selectively with any member of the Ras superfamily of monomeric GTPases.

The process of directing proteins towards and into the mitochondrion, mediated by mitochondrial proteins that recognize signals contained within the imported protein.

The cleavage of proteins, usually near the N terminus, during the process of import into the mitochondrion; several different peptidases mediate cleavage of proteins destined for different mitochondrial compartments.

extracellular ligand-gated ion channel activity

The chemical reactions involving lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. Includes fatty acids; neutral fats, other fatty-acid esters, and soaps; long-chain (fatty) alcohols and waxes; sphingoids and other long-chain bases; glycolipids, phospholipids and sphingolipids; and carotenes, polyprenols, sterols, terpenes and other isoprenoids.